PerkinElmer Genetics

Specimen Collection Guidelines

• Specimens should be collected at the same time as the specimen for state mandated testing. The ideal time for collection is between 24-48 hours of age.
• If the newborn is discharged before 24 hours of age, a repeat specimen should be collected at about 48 hours of age from the pediatrician. Critically ill newborns should be screened before 48 hours of age.
• A pre-transfusion specimen is essential. If this is impossible, obtain one specimen at 24-48 hours of age and a repeat specimen 3 days after the last transfusion.
• If an initial screen is obtained prior to transfusion when the newborn is older than 24 hours of age, a repeat specimen is not necessary.
• Screening can be done on patients of any age utilizing the filter paper cards with the exception of Cystic Fibrosis screen which is not valid after three months of age.
• Air-dry the filter paper on a flat surface for three to four hours. Do not heat, stack, or allow the blood spots on the filter paper to touch other surfaces during the drying process.
• If specimens cannot be sent for analysis immediately, store them in a plastic bag in a freezer (preferably) or a refrigerator.